Can a pill mimic the benefits of fasting?

Fasting and calorie reduction have strong evidence for extending healthy lifespan in animals. Researchers are testing compounds — including metformin, spermidine, and NAD+ boosters — that may reproduce some of these benefits without requiring extreme dietary restriction. Human trials are ongoing.

Promising early evidence; full human proof is still pending for most compounds

Food & Lifestyle · tracking since 2026-03-14