"Could a new pill help you lose weight safely?"
Foundayo is a new oral weight loss medication that helps people lose significant weight and improve heart health.
large human trialsignificant
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The whole archive, filed by the part of life it belongs to — and labelled with how strong the evidence behind it actually is.
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Foundayo™ (orforglipron), Lilly's new oral GLP-1 pill for weight loss, now available in the U.S.
Lilly has launched Foundayo™ (orforglipron), an oral GLP-1 receptor agonist for weight management, now available in the U.S. This innovative treatment is nota...
significant
Scientists discover hidden gut trigger behind ALS and dementia
Researchers at Case Western Reserve University have identified a significant link between gut bacteria and the progression of Amyotrophic Lateral Sclerosi...
significant
PANoptosis in the Aging of the Heart
PANoptosis emerges as a critical programmed cell death mechanism in the context of cardiac aging, as highlighted in a recent review. This mode of cell death i...
noteworthy
High Dose Influenza Vaccine Correlates with Greater Reduction in Dementia Risk
A recent retrospective cohort study utilizing data from the IQVIA PharMetrics Plus for Academics database has revealed that high-dose inactivated influenza va...
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Leads Biolabs’ Opamtistomig (PD-L1/4-1BB Bispecific Antibody) Advances to Expansion Phase in First-Line Biliary Tract Cancer Following Positive Safety and Preliminary Efficacy Results
Nanjing Leads Biolabs Co., Ltd. has announced the successful completion of the safety run-in stage of a Phase II clinical trial for its bispecific antibody, O...
Your DNA has a secret “second code” that decides which genes get silenced
Researchers from Kyoto University and RIKEN, led by Osamu Takeuchi and Takuhiro Ito, have uncovered a previously unrecognized layer of genetic regulatio...
Losing Your Voice? Millions Experience Persistent Problems Each Year
The American Speech-Language-Hearing Association (ASHA) is amplifying awareness of vocal health in recognition of World Voice Day on April 16, 2026. With the th...
Ecuador Free of Rabies project accelerates progress toward eliminating dog-mediated rabies supported by Boehringer Ingelheim’s Stop Rabies program
Ecuador is making significant strides towards becoming one of the first rabies-free countries in Latin America, with a targeted goal to eliminate dog-mediated r...
Kainova Therapeutics Expands Phase I/II Trial of DT-7012, a Treg-depleting Anti-CCR8 Antibody, with First Patient Dosed in Europe
Kainova Therapeutics has initiated the European expansion of its DOMISOL Phase I/II clinical trial, marking a key milestone in the global development of DT-70...
The hidden tradeoff behind today’s most popular weight loss drugs
Recent research from Vanderbilt University Medical Center reveals that both weight loss drugs (specifically GLP-1 receptor agonists like semaglutide and tir...
significant
Scientists discover spice synergy that boosts anti-inflammation 100x
Researchers at Tokyo University of Science, led by Professor Gen-ichiro Arimura, have unveiled a significant breakthrough in understanding the synergi...
NeuroTherapia completes Phase 2a trial of NTRX-07 in Alzheimer’s
NeuroTherapia, Inc. has successfully completed a 28-day double-masked Phase 2a trial for its oral candidate, NTRX-07, targeting patients with Alzheimer’...
significant
Airna doses first patient in Phase 1 trial of AIR-001 for AATD
Airna has initiated a Phase 1 clinical trial for AIR-001, an RNA-editing therapeutic targeting alpha-1 antitrypsin deficiency (AATD). The open-label RepAIR1...
significant
AliveCor expands AI 12-lead cardiac diagnostics to Vietnam
AliveCor has achieved regulatory registration in Vietnam for its Kardia 12L electrocardiogram system, which integrates KAI 12L AI technology. This porta...
Life Biosciences secures $80 million Series D financing
Boston-based Life Biosciences has successfully closed an $80 million Series D financing, fully subscribed, which will bolster operations through the latter...
significant
Breakthrough water filter removes 98% of toxic PFAS forever chemicals
Researchers at Flinders University, led by Dr. Witold Bloch, have developed an innovative nano-sized molecular cage that effectively captures short-ch...
significant
This “rotten egg” brain gas could be the key to fighting Alzheimer’s disease
Researchers at Johns Hopkins Medicine have identified a critical role for the protein Cystathionine γ-lyase (CSE) in the production of trace amounts of...
significant
Your brain could help solve autism and most people don’t know it
A recent survey conducted by Autism BrainNet reveals a significant gap in public understanding regarding the role of brain donation in autism research....
significant
Barriers and facilitators to recruiting older adult care home residents into clinical trials of medicines and vaccines: a scoping review
A recent scoping review from the Widening Access to Trials in Care Homes project highlights critical barriers and facilitators to recruiting care home (CH) resi...
significant
Consistent benefit of physiology-guided complete revascularization across the spectrum of frailty in older patients with myocardial infarction: a prespecified analysis of the FIRE trial
A recent analysis from the FIRE trial, involving 1,445 patients aged ≥75 years with myocardial infarction (MI) and multivessel disease, has revealed critica...
significant
Daily briefing: A treatment to reverse cellular ageing is about to be tested in people
A recent study has demonstrated that a single DNA modification in a non-coding region of the X chromosome, specifically enhancer 13 (En13), can induce sex...
Frequent in dementia, deadliest without it: delirium and mortality in hospitalised older adults
A recent multicenter cohort study involving 2,556 hospitalized adults aged 65 and older across five countries (Brazil, Angola, Chile, Colombia, and Portugal) ha...
significant
Glycemic Control Targets in Older Adults with Type 2 Diabetes and Chronic Kidney Disease: A Trajectory-Based Survival Analysis of HbA1c
A recent retrospective multicenter cohort study utilizing the Tianjin Health and Medical Big Data Super Platform has revealed critical insights into glycemic ma...
significant